Established in 1884, the International & Great Northern Railway Employees' Hospital Association built a complex of frame structures at this site adjacent to the railroad tracks. The hospital, which operated on monthly employee dues, provided service to all railroad employees along the I&GN lines. In 1920 the frame structures were razed and replaced with a new brick hospital building. In addition to patient rooms, the institution included a pharmacy, laboratories, medical clinic, and emergency room with ambulance service. An adjacent two-story nurses' quarters building was added to the site in 1925. Designed by prominent Houston architect Alfred C. Finn, both buildings exhibit elements of Georgian Revival style architecture. Prominent features of the hospital include its raised basement, central bay, and ornate Georgian portico. The nurses' quarters features an offset classical portico and hipped roof. The Missouri-Pacific Railroad took over the I&GN lines in the 1930s, and after that time the institution was known as the Missouri-Pacific Lines Hospital Association. The hospital continued to operate until 1970. The buildings stand as reminders of the railroad's impact on the City of Palestine. Recorded Texas Historic Landmark - 1990